Neuropathy Repair in Lyme Disease
In chronic Lyme disease, with or without the coinfections of babesia and bartonella, it is common to have nerve injury. In this video and written article Marty Ross MD discusses steps to repair the tingling, numbness, and pain that occur in this condition. These steps include
- treating infections,
- repairing nerve cell and mitochondria power plant membranes,
- increasing the master cell repair antioxidant glutathione,
- increasing the nutrient Coenzyme Q 10 (Co Q10),
- taking acetyl l carnitine if you do not eat red meat, and
- decreasing inflammation.
The three major infections seen in Lyme disease (borrelia (Lyme), bartonella, and babesia can lead to nerve injury. Of these, borellia and bartonella have a greater chance of causing this condition. For information on treating the infections see: A Lyme Disease Antibiotic Guide, Kills Bartonella: A Brief Guide, and Kills Babesia: A Brief Guide.
Marty Ross MD Discusses Neuropathy Repair.
The video is a recording from our webinar Conversations with Marty Ross MD recorded in 2016 when Dr. Ross practiced in Seattle, Washington.
In neuropathy often the outer membrane of the nerve cell is damaged. This membrane is composed of a phospholipid fats called phosphatidylcholine and phospatidylserine.
Sometimes the energy factories found in nerve cells (and in every other type of cell) called mitochondria also get injured. When the mitochondria are injured, nerves cannot generate enough energy to repair. In mitochondrial injury the outer membrane of the mitochondria is damaged. This membrane too is composed of phosphatidylcholine and phosphatidylserine.
There are three products I suggest that include mitochondria membrane fats. These products are all manufactured by Researched Nutritionals. These products are NT Factor Energy, ATP Fuel, and ATP 360. Each of these products contains types of fats shown to repair and support the mitochondria membranes. They also include various micronutrients that support mitochondria function.
NT Factor Energy and ATP Fuel include a proprietary blend of phosphatidyl serine and phospatidyl choline made by another company called NT Factor. In studies with people reporting fatigue, NT Factor in both of these products is shown to improve energy at two months by an average of 40%. ATP Fuel contains Co Q10, but NT Factor Energy does not. Co Q10 should not be used in Babesia treatments that include atovaqone (Mepron and Malarone) because it interferes with theire ability to kill this germ.
ATP 360 does not use NT Factor as its fat source. Instead, Researched Nutritionals includes its own proprietary phospholipid formula and delivery system. ATP 360 does include ingredients that are shown to increase the mass of the mitochondria. Finally ATP 360 also includes Co Q10. In unpublished studies by Researched Nutritionals, ATP 30 and ATP Fuel are shown to work as well at improving energy. ATP 360 is easier to take because it requires one time a day doseing.
Choose one of the products below based on the information above. Do not use two or more of these products together at the same time.
- NT Factor Energy take 2 pills 3 times a day for 2 months, then decrease to 1 pill 3 times a day for 4 months.
- ATP Fuel take 5 pills 2 times a day for 6 months.
- ATP 360 take 3 pills 1 time a day for 6 months.
NT Factor Energy is the only product to take if a person is on atovaqone found in Mepron and Malarone to treat babesia.
Glutathione is a powerful antioxidant that repairs cell injury. It is made in every cell. Liposomal glutathione is the best form. This type of glutathione is microscopically wrapped in phospholipid fats which increases its absorption. One can also breath glutathione in using a nebulizer or take it by IV. The nebulizer and IV versions may work more effectively in some than the liposomal oral form. Read more about the nebulizer and IV versions including dosing and how frequent to take them in the article Glutathione: The Great Fixer.
An alternative to glutathione is to take a building block of glutathione called N acetyl-cysteine (NAC). Inside cells NAC is used to make glutathione. My preference is liposomal glutathione but in some it does not work or is too expensive.
- Liposomal Glutathione 500mg/5ml take 5ml 1 or 2 times a day, or
- N Acetyl-Cysteine (NAC) 500mg 1 pill 3 times a day.
Add Co Q10
Co Q10 is a key nutrient used in chemical reactions inside mitochondria that create cell fuel. Most people do not get enough of this essential nutrient in their diets.
- Co Q10 400mg 1 pill 2 times a day.
Carnitine is a transport vehicle that carries fat to the inside of a mitochondria so that it can be burned into cell fuel through chemical reactions. The key source of carnitine is red meat. So if a person does not eat red meat, they may not be able to fuel up mitochondria. The most absorbed and used source of carnitine is acetyl-l-carnitine.
- Acetyl-L-Carnitine 500mg 1 pill 2 times a day for 1 month and then 1 pill daily.
Decrease Nerve Inflammation
To lower nerve inflammation caused by inflammatory cytokines take curcumin which is a component of the seasoning turmeric. Read more about curcumin on this site. Be sure to use a liposomal variety of curcumin. Liposomal curcumin is wrapped microscopically in fat which increases absorption.
- Curcumin 500mg 1 pill 3 times a day.
Heavy Metal Detoxification
Heavy metals like lead and mercury can injure nerves. By six months doing the above, if there is inadequate improvement, then consider testing for heavy metal toxicity. If heavy metals are elevated then a chelating agent can lower the metals. Read more about this in Heavy Metals: The Problem and Best Test.
Give It Time
Nerve repair takes time. Give this protocol at least six months to see if it will help.